Median rates of genome instability events (/10⁷ cell divisions).

<p>The median rate (95% confidence of intervals) of the different genome instability events was measured as described in the text and in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113435#pone-0113435-g001" target="_blank">Fig. 1</a>; the numbers in superscript (for example ⁶) correspond to the number of repeats. The MMS concentration was 1 mM as described under Material and methods. Allelic recombination, total LOH and chromosome loss were measured in diploid cells; chromosome gain was measured in haploid cells. The rates in the <i>wpl1</i> mutants was previously found to not differ statistically from WT (also found there the rate for <i>mcd1-1</i> haploid cells <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113435#pone.0113435-Covo2" target="_blank">[15]</a>). ND – not determined. * indicates a rate lower than indicated, a rate of 5 events per 10⁸ cell divisions was a rate that could be accurately measured using this assay.</p><p>Median rates of genome instability events (/10⁷ cell divisions).