Proportions of functional activity profiles for <i>T. cruzi</i>-specific CD8⁺ T cell subsets from CCPs.

<p>Functional profiles of CD8⁺ T cell subsets stimulated with Staphylococcal enterotoxin B (SEB) and parasite lysate are color-coded according to the number of functions and summarised in the pie charts. Each pie slice corresponds to the mean production of one (dark grey), two (light grey) and three (red) functions. The white pie corresponds to the absence of a response when IFN-γ, TNF-α and IL-2 production were observed. CCPs were grouped according to their disease severity as described in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003432#s2" target="_blank">Materials and Methods</a> (A = 8, B = 6, C = 6 and D = 4).