Detection of dissemination of <i>B. pseudomallei</i> mutants by optical imaging.

<p>Groups of 5 female albino C57BL/6J mice were challenged by the IMIT route of infection with either wild type luminescent <i>B. pseudomallei</i> strain JW280, the Δ<i>wcb</i> capsule mutant, or the Δ<i>sctU</i>_Bp3 T3SS3 mutant. Representative images of disease endpoints are presented, with uniform image settings adjusted to a range of 2.5×10³ to 3×10⁴ p/s/cm2/sr on a logarithmic scale.