<p>Groups of 3 male albino C57BL/6J mice were challenged with increasing doses of luminescent <i>B. pseudomallei</i> strain JW280 by IMIT infection. Mice were monitored for 14 days (336 hr) for disease progression and euthanized at the onset of moribund disease presentation. Survival curves are used to present the dose-dependent response of the host to increasing bacterial challenges. The MTTD was calculated for groups with ≥50% mortality, as indicated.</p
<p>Mice were administered mAb(s) by the i.p. route followed 18 h later by i.n. challenge with 15 LD<...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
<p>Groups of 5 female albino C57BL/6J mice were challenged with increasing doses of luminescent <i>B...
<p>Percentage of survival of BALB/c mice challenged intranasally with 2 LD<sub>50</sub> (panel A), 3...
Mouse models have been essential to generate supporting data for the research of infectious diseases...
Mouse models have been essential to generate supporting data for the research of infectious diseases...
Plot of dose response curves for each B. pseudomallei clinical isolate in (A) BALB/c mice and (B) C5...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
Burkholderia pseudomallei is the aetiological agent of melioidosis, a life-threatening bacterial dis...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<div><p><i>Burkholderia pseudomallei</i>, the etiologic agent of melioidosis, is a Gram negative bac...
Melioidosis is a potentially fatal disease caused by the bacterium, Burkholderia pseudomallei. The c...
<p>The survival rate of mice receiving inoculations of various doses (10<sup>1</sup>–10<sup>6</sup>)...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
<p>Mice were administered mAb(s) by the i.p. route followed 18 h later by i.n. challenge with 15 LD<...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
<p>Groups of 5 female albino C57BL/6J mice were challenged with increasing doses of luminescent <i>B...
<p>Percentage of survival of BALB/c mice challenged intranasally with 2 LD<sub>50</sub> (panel A), 3...
Mouse models have been essential to generate supporting data for the research of infectious diseases...
Mouse models have been essential to generate supporting data for the research of infectious diseases...
Plot of dose response curves for each B. pseudomallei clinical isolate in (A) BALB/c mice and (B) C5...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
Burkholderia pseudomallei is the aetiological agent of melioidosis, a life-threatening bacterial dis...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<div><p><i>Burkholderia pseudomallei</i>, the etiologic agent of melioidosis, is a Gram negative bac...
Melioidosis is a potentially fatal disease caused by the bacterium, Burkholderia pseudomallei. The c...
<p>The survival rate of mice receiving inoculations of various doses (10<sup>1</sup>–10<sup>6</sup>)...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
<p>Mice were administered mAb(s) by the i.p. route followed 18 h later by i.n. challenge with 15 LD<...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...
Burkholderia pseudomallei, the etiological agent of melioidosis, causes significant mortality in end...