<p>CLK1, SRPK1, SRPK2, and SRPK3 assays were performed with 5 µM ATP, and the CLK2 assay was performed with 20 µM ATP. The definition and determination of the IC<sub>50</sub> values are described in the Methods.</p><p>Specificity of the kinase inhibitors for CLK1, CLK2, SRPK1, SRPK2, and SRPK3.</p
Substrate-competitive kinase inhibitors represent a promising class of kinase inhibitors, however, t...
SummarySmall-molecule inhibitors of protein and lipid kinases have emerged as indispensable tools fo...
Protein kinases are enzymes that catalyse the phosphoryl transfer from the g-phosphate of ATP to acc...
Phosphorylation events catalyzed by protein kinases represent one of the most prevalent as well as i...
The specificities of 28 commercially available compounds reported to be relatively selective inhibit...
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of ...
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases h...
Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been li...
AbstractThe specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhib...
<p>(A) Kinase assay of Cdk4 (10 ng) was performed with Cdk4 inhibitors 8A and 8B at different doses ...
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of ...
Substrate-competitive kinase inhibitors represent a promising class of kinase inhibitors, however, t...
SummarySmall-molecule inhibitors of protein and lipid kinases have emerged as indispensable tools fo...
Protein kinases are enzymes that catalyse the phosphoryl transfer from the g-phosphate of ATP to acc...
Phosphorylation events catalyzed by protein kinases represent one of the most prevalent as well as i...
The specificities of 28 commercially available compounds reported to be relatively selective inhibit...
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of ...
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases h...
Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been li...
AbstractThe specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhib...
<p>(A) Kinase assay of Cdk4 (10 ng) was performed with Cdk4 inhibitors 8A and 8B at different doses ...
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of ...
Substrate-competitive kinase inhibitors represent a promising class of kinase inhibitors, however, t...
SummarySmall-molecule inhibitors of protein and lipid kinases have emerged as indispensable tools fo...
Protein kinases are enzymes that catalyse the phosphoryl transfer from the g-phosphate of ATP to acc...