Aortic expression of VSMC markers in wild-type and MGP<sup>-/-</sup> mice.
- Rajeev Malhotra (392121)
- Megan F. Burke (684687)
- Trejeeve Martyn (684688)
- Hannah R. Shakartzi (684689)
- Timothy E. Thayer (684690)
- Caitlin O’Rourke (684691)
- Pingcheng Li (585338)
- Matthias Derwall (468293)
- Ester Spagnolli (684692)
- Starsha A. Kolodziej (684693)
- Konrad Hoeft (684694)
- Claire Mayeur (684695)
- Pawina Jiramongkolchai (684696)
- Ravindra Kumar (524606)
- Emmanuel S. Buys (392112)
- Paul B. Yu (94676)
- Kenneth D. Bloch (390983)
- Donald B. Bloch (468296)
Publication date
January 2015
DOIAbstract
<p>RNA was isolated from aortas of WT and MGP<sup>-/-</sup> mice and from LDN-193189-treated MGP<sup>-/-</sup> mice at 7 and 14 days of age (n = 4–8 in each group). Levels of mRNAs encoding myocardin, α smooth muscle actin (SMA), transgelin, and calponin are depicted. The aortas of 14-day-old MGP<sup>-/-</sup> mice have decreased expression of VSMC markers compared to WT mice. Treatment with LDN-193189 did not restore the expression of VSMC markers to WT levels. # P<0.05 compared to 7-day-old MGP<sup>-/-</sup> mice.</p
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