<p>(A) Bacterial burden in LN (circles) and ears (triangles) harvested at 24 hpi from mice inoculated with bacteria grown at 26°C (225 CFU, black) or 37°C (283 CFU, white). (B) Bacterial burden in LN (circles), spleens (squares) and ears (triangles) harvested at 48 hpi from mice inoculated with bacteria grown at 26°C (453 CFU, black) or 37°C (290 CFU, white). For (A) and (B), each symbol represents bacterial burden from a single mouse. Horizontal bars are the median of the group. The dotted line represents the limit of detection. Statistical significance was determined using the Mann Whitney test and the p value is shown. Differences between groups were considered to be statistically significant when p < 0.05. (C) Bacterial burden in LNs at...
<p>(A, B) H&E-stained sections of formalin-fixed LN tissue from uninfected (A) and infected (B) anim...
<p>Mice were infected subcutaneously with 1×10<sup>4</sup> cfu of either Kim53pGFP (black symbols) o...
<p>Mice were vaccinated and challenged as described in <a href="http://www.plosone.org/article/info:...
<p>(A and B) Southern dot blot analysis of DNA from bacteria from (A) LNs harvested at 12 hpi and (B...
<p>Mice were inoculated with RFP-<i>Y. pestis</i> and the ear pinna was removed along with surroundi...
<p>C57BL/6 mice were infected by intraperitoneal injection (10<sup>6</sup> bacteria/mouse), intragas...
<p>Treatment with GEN at 25 mg/kg q24h (filled circles), CIN at 30 mg/kg q12h (open circles) and CIN...
<p>C57BL/6 mice were infected by gavage with 10<sup>9</sup>, 10<sup>8</sup> or 10<sup>7</sup><i>B</i...
<p>Bacteria were suspended in PBS to optical densities of 1X10<sup>6</sup> (Dose 1), 1X10<sup>5</sup...
<p>Mice were infected id in the ear with 5x10<sup>3</sup> cfu of each strain. At 48 h post infection...
<p>BALB/c mice (n = 8–10 animals per time point) were inoculated orally with 5×10<sup>5</sup> CFU Bp...
<p>(A) Neutrophils at the IS at different time points. A diagram summarizing the events per time poi...
<p>Mice were challenged with D39, D39Δ<i>spd1837</i>, D39Spd1837<sub>C8S,</sub> D39Δ<i>spd1838</i>, ...
<p><b>A</b>) At least 90% of spores in the inoculum germinated 24 hours post infection of ear pinnas...
<p>(A) Bacterial colony forming unit (CFU) counts from the blood of mice grafted with human skin and...
<p>(A, B) H&E-stained sections of formalin-fixed LN tissue from uninfected (A) and infected (B) anim...
<p>Mice were infected subcutaneously with 1×10<sup>4</sup> cfu of either Kim53pGFP (black symbols) o...
<p>Mice were vaccinated and challenged as described in <a href="http://www.plosone.org/article/info:...
<p>(A and B) Southern dot blot analysis of DNA from bacteria from (A) LNs harvested at 12 hpi and (B...
<p>Mice were inoculated with RFP-<i>Y. pestis</i> and the ear pinna was removed along with surroundi...
<p>C57BL/6 mice were infected by intraperitoneal injection (10<sup>6</sup> bacteria/mouse), intragas...
<p>Treatment with GEN at 25 mg/kg q24h (filled circles), CIN at 30 mg/kg q12h (open circles) and CIN...
<p>C57BL/6 mice were infected by gavage with 10<sup>9</sup>, 10<sup>8</sup> or 10<sup>7</sup><i>B</i...
<p>Bacteria were suspended in PBS to optical densities of 1X10<sup>6</sup> (Dose 1), 1X10<sup>5</sup...
<p>Mice were infected id in the ear with 5x10<sup>3</sup> cfu of each strain. At 48 h post infection...
<p>BALB/c mice (n = 8–10 animals per time point) were inoculated orally with 5×10<sup>5</sup> CFU Bp...
<p>(A) Neutrophils at the IS at different time points. A diagram summarizing the events per time poi...
<p>Mice were challenged with D39, D39Δ<i>spd1837</i>, D39Spd1837<sub>C8S,</sub> D39Δ<i>spd1838</i>, ...
<p><b>A</b>) At least 90% of spores in the inoculum germinated 24 hours post infection of ear pinnas...
<p>(A) Bacterial colony forming unit (CFU) counts from the blood of mice grafted with human skin and...
<p>(A, B) H&E-stained sections of formalin-fixed LN tissue from uninfected (A) and infected (B) anim...
<p>Mice were infected subcutaneously with 1×10<sup>4</sup> cfu of either Kim53pGFP (black symbols) o...
<p>Mice were vaccinated and challenged as described in <a href="http://www.plosone.org/article/info:...