Mortalin <i>ab initio</i> models.

<p>The mortalin SAXS curve was used by calculating 20 low-resolution <i>ab initio</i> models using the DAMMIN software, and these were merged using the DAMAVER package. The result is the final <i>ab initio</i> model presented in several orientations (<b>A</b>). Manual superposition of the crystallographic structures of the mortalin NBD (PDB acc. no. 4KBO—magenta) and PBD of the <i>E. coli</i> DnaK (PDB acc. no. 1DKX—blue) into the <i>ab initio</i> model (<b>B</b>). Manual superposition of the crystallographic structure of the full length <i>E. coli</i> DnaK (PDB acc. n. 4B9Q—blue) into the mortalin <i>ab initio</i> model (<b>C</b>). Figures generated by the UCSF Chimera software (version 1.9).