Body weight and cumulative food consumption in sedentary and wheel-running mice.

<p>(A) Body weight in mice housed in a sedentary condition (SED; unfilled circles) or given free-access to a running-wheel (RW; filled circles) throughout experimental period. Mice were weighed weekly between ZT2 and ZT3 and data are shown as means ± SEM (<i>n</i> = 28). (B) Cumulative food consumption during light (ZT0–12) and dark (ZT12–24) period in SED (unfilled bar) and RW (filled bar) mice. Food consumption by mice was measured daily during the fourth week of access to running-wheels. Data are shown as means ± SEM (<i>n</i> = 14). *<i>P</i> < 0.01, significant differences between RW and SED mice. ZT, Zeitgeber time.