Nox1 knockdown did not affect the proliferation of progenitor cells in the SVZ after cerebral ischemia.

<p>(a) Representative photomicrograph of BrdU or Ki67 immunostaining showing proliferating cells in the SVZ area at 2 weeks after ischemia—reperfusion. BrdU and Ki67 coexpression in the SVZ is demonstrated as purple staining after merging red (Ki67) and blue (BrdU) images. Scale bars = 30 μm. (b) Schematic diagrams of the infarct core and the peri-infarct region delineated by Nissl staining at 2 weeks after MCAO—reperfusion. Black: infarct core; black dotted line: peri-infarct region; gray colored boxe: BrdU and Ki67 immunostaining observed areas (c) BrdU- and Ki67-stained cells were counted in the ischemia—reperfusion brain. Results are presented as mean ± SEM, n = 6/6. **p<0.01 vs the scbRNA control. scbRNA: scramble shRNA; control: sham control.