Body weights and blood glucose levels of C57BL/6J mice.

<p>(A) Appearances of control diet- and high-fat diet-fed C57BL/6J mice in the 12-month subgroups. Time courses of changes in body weight (B) and blood glucose levels (C) from baseline (n = 15 each for high-fat diet and control diet, 8 weeks old) at 1 month (n = 15 each for high-fat diet and control diet), at 3 months (n = 10 each for high-fat diet and control diet), at 5 months (n = 5 each for high-fat diet and control diet), and at 12 months (n = 5 each for high-fat diet and control diet) from starting the experiment. Results are means ± SEM ***P < 0.001 high-fat diet group vs. control diet group. Ctrl, control diet group; HFD, high-fat diet group.