<p>Mice were infected i.t. with 5×10<sup>7</sup> CEA10 conidia and at indicated time-points, mice were euthanized, bronchoalveolar lavage fluid (BALF) collected, and lung tissue homogenized. IL-1β <b>(A)</b>, IL-18 <b>(B)</b>, IL-1α <b>(C)</b>, and IL-1Ra <b>(D)</b> levels in lung homogenate (IL-1α) and BALF (IL-1β, IL-18, and IL-1Ra) were measured using ProcartaPlex Mouse Cytokine & Chemokine 36-plex Immunoassay or ELISA. Data are representative of four mice per time point and two independent experiments. Each dot represents the mean ± one SEM.</p
<p>C57BL/6 mice were infected intranasally with <i>A. fumigatus</i> and treated intraperitoneally wi...
<p>A. BAL cells were stained with Wright-Giemsa stain and examined under a light microscope after in...
<p>(<b>A</b>) 8–12 week old B6 or <i>Il1r1<sup>−/−</sup></i> mice were infected with 1×10<sup>6</sup...
<p>C57BL/6 mice were infected intranasally with different strains of <i>A. fumigatus</i> (6 mice/gro...
<p>C57BL/6 mice treated with isotype control antibody or IL-1α neutralizing antibody were infected i...
<p>A. Mice were infected intratracheally with 2×10<sup>7</sup><i>A. fumigatus</i> conidia. At specif...
<p>C57BL/6 mice treated with either isotype control antibody or IL-1α neutralizing antibody, <i>Il1r...
<p>C57BL/6 mice were infected intranasally with different strains of <i>A. fumigatus</i> (6 mice/gro...
<p>Age-matched C57BL/6 or <i>Il1r1</i>-deficient mice were infected i.t. with 5×10<sup>7</sup> CEA10...
<p><b>A.</b> A survival analysis was performed comparing wild-type (n = 8), Caspase 1<sup>-/-</sup> ...
<p>C57BL/6 (B6) or B6.C3H-<i>sst1</i> congenic mice were infected with <i>C. pneumoniae</i> (Cp) as ...
<p>Mice were administered <i>A. fumigatus</i> (1.25×10<sup>7</sup> conidia per mouse) by oropharynge...
<p>A. Representative lung sections from VitD+ and VitD- mice three days post intratracheal challenge...
<p>B6 mice treated with isotype control (ISO) or anti-Gr-1 (α-Gr-1) antibody were infected with Δ<i>...
<p><b>A.</b> Histology of fixed H&E stained lung sections from mice at 24 hpi with <i>Y</i>. <i>pest...
<p>C57BL/6 mice were infected intranasally with <i>A. fumigatus</i> and treated intraperitoneally wi...
<p>A. BAL cells were stained with Wright-Giemsa stain and examined under a light microscope after in...
<p>(<b>A</b>) 8–12 week old B6 or <i>Il1r1<sup>−/−</sup></i> mice were infected with 1×10<sup>6</sup...
<p>C57BL/6 mice were infected intranasally with different strains of <i>A. fumigatus</i> (6 mice/gro...
<p>C57BL/6 mice treated with isotype control antibody or IL-1α neutralizing antibody were infected i...
<p>A. Mice were infected intratracheally with 2×10<sup>7</sup><i>A. fumigatus</i> conidia. At specif...
<p>C57BL/6 mice treated with either isotype control antibody or IL-1α neutralizing antibody, <i>Il1r...
<p>C57BL/6 mice were infected intranasally with different strains of <i>A. fumigatus</i> (6 mice/gro...
<p>Age-matched C57BL/6 or <i>Il1r1</i>-deficient mice were infected i.t. with 5×10<sup>7</sup> CEA10...
<p><b>A.</b> A survival analysis was performed comparing wild-type (n = 8), Caspase 1<sup>-/-</sup> ...
<p>C57BL/6 (B6) or B6.C3H-<i>sst1</i> congenic mice were infected with <i>C. pneumoniae</i> (Cp) as ...
<p>Mice were administered <i>A. fumigatus</i> (1.25×10<sup>7</sup> conidia per mouse) by oropharynge...
<p>A. Representative lung sections from VitD+ and VitD- mice three days post intratracheal challenge...
<p>B6 mice treated with isotype control (ISO) or anti-Gr-1 (α-Gr-1) antibody were infected with Δ<i>...
<p><b>A.</b> Histology of fixed H&E stained lung sections from mice at 24 hpi with <i>Y</i>. <i>pest...
<p>C57BL/6 mice were infected intranasally with <i>A. fumigatus</i> and treated intraperitoneally wi...
<p>A. BAL cells were stained with Wright-Giemsa stain and examined under a light microscope after in...
<p>(<b>A</b>) 8–12 week old B6 or <i>Il1r1<sup>−/−</sup></i> mice were infected with 1×10<sup>6</sup...