<p>* Novel mutations detected</p><p>Spectrum of mutations in the ABL KD and SH3-SH2 domain of BCR/ABL gene according to the disease phase.</p
Cartoon diagrams of RAD52, BRCA2, BRCA1 and PALB2 showing specific domains in each gene. The diagram...
Parts of the Bcr/Abl hybrid transcript supposed to be important for its transforming ability were se...
Mutations in the Bcr-Abl kinase domain (KD) are often detected at the time of resistance to tyrosine...
<p>(Top) Compound mutations are double mutants that arise in the same clone and are detected in trea...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Background: The BCR-ABL1 tyrosine kinase domain mutation constitutes a major cause of resistance to ...
<p>Comparison of the frequencies of pre-existing BCR-ABL KD mutations and mutations detected after m...
Emergence of clones carrying point mutations in the BCR-ABL1 kinase domain (KD) is a common mechanis...
The introduction of tyrosine kinase inhibitors (TKIs), starting with imatinib and followed by second...
Background Mutations in the ABL kinase domain and SH3-SH2 domain of the BCR/ABL gene and ampli-ficat...
<p>Epidermal growth factor receptor (EGFR) mutation spectrum among patients with EGFR-mutant lung ad...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder whose hallmark is represe...
<p>(A) Sanger sequencing chromatograms showing confirmed SPRY4 variants. (B) Domain structure of the...
Cartoon diagrams of RAD52, BRCA2, BRCA1 and PALB2 showing specific domains in each gene. The diagram...
Parts of the Bcr/Abl hybrid transcript supposed to be important for its transforming ability were se...
Mutations in the Bcr-Abl kinase domain (KD) are often detected at the time of resistance to tyrosine...
<p>(Top) Compound mutations are double mutants that arise in the same clone and are detected in trea...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Background: The BCR-ABL1 tyrosine kinase domain mutation constitutes a major cause of resistance to ...
<p>Comparison of the frequencies of pre-existing BCR-ABL KD mutations and mutations detected after m...
Emergence of clones carrying point mutations in the BCR-ABL1 kinase domain (KD) is a common mechanis...
The introduction of tyrosine kinase inhibitors (TKIs), starting with imatinib and followed by second...
Background Mutations in the ABL kinase domain and SH3-SH2 domain of the BCR/ABL gene and ampli-ficat...
<p>Epidermal growth factor receptor (EGFR) mutation spectrum among patients with EGFR-mutant lung ad...
Patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) frequently r...
Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder whose hallmark is represe...
<p>(A) Sanger sequencing chromatograms showing confirmed SPRY4 variants. (B) Domain structure of the...
Cartoon diagrams of RAD52, BRCA2, BRCA1 and PALB2 showing specific domains in each gene. The diagram...
Parts of the Bcr/Abl hybrid transcript supposed to be important for its transforming ability were se...
Mutations in the Bcr-Abl kinase domain (KD) are often detected at the time of resistance to tyrosine...
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