<p>Whilst no apoptosis was identified in islets from LFD controls (A), TUNEL-positive cells were found in pancreatic tissues from HFD fed mice (B-E), but were not different between treatment groups (F). Of note, special attention was paid to assess peri-insulitis and none was identified. Scale bar = 10 μm.</p
<p>Four weeks after the cessation of OA treatment, fresh islets were isolated from T2D mice treated ...
<p>Mice were treated with a treat-to-target insulin therapy for a month and tested with intraperiton...
<p>Representative images of pancreas section stained for Ki67 of control group (A) and HFD-PBS (B), ...
<p>A-C) 500 Islets, D-F) 500 Islets + cytokines, G-I) 500 Islets +1.0×10<sup>6</sup> bMSCs, + cytoki...
<p>Representative images of pancreas section stained for caspase-3 of control group (A) and HFD-PBS ...
<p><b>(a-p)</b> TUNEL labelling of pancreatic islets exposed to IL-1β, IFN-γ, and TNF-α for 24 hours...
Prophylactic insulin treatment has been shown to have beneficial effects in type 1 diabetes, both in...
<p>Mice were treated with Ad-m IL-10/Ad-m IGF-1. Pancreata were collected at 3 weeks after treatment...
<p>Composition of the insulitic lesion in 4-wk old diabetes-prone (islets from 5 mice), 12-wk old in...
Although insulin-dependent diabetes mellitus (IDDM) results from irreversible loss of beta cells, th...
<p>A Representative islets showing insulin (red) and Ki67 (green, indicated by arrows), insulin (red...
<p>Histology of representative pancreas sections of NOD mice before (at the commencement of autoimmu...
Prophylactic insulin treatment has been shown to have beneficial effects in type 1 diabetes, both in...
(A) Representative images of the pancreatic tissues from different groups were examined using H&E st...
<p>Representative frozen sections from a 3 week old female pre diabetic NOD mouse without insulitis ...
<p>Four weeks after the cessation of OA treatment, fresh islets were isolated from T2D mice treated ...
<p>Mice were treated with a treat-to-target insulin therapy for a month and tested with intraperiton...
<p>Representative images of pancreas section stained for Ki67 of control group (A) and HFD-PBS (B), ...
<p>A-C) 500 Islets, D-F) 500 Islets + cytokines, G-I) 500 Islets +1.0×10<sup>6</sup> bMSCs, + cytoki...
<p>Representative images of pancreas section stained for caspase-3 of control group (A) and HFD-PBS ...
<p><b>(a-p)</b> TUNEL labelling of pancreatic islets exposed to IL-1β, IFN-γ, and TNF-α for 24 hours...
Prophylactic insulin treatment has been shown to have beneficial effects in type 1 diabetes, both in...
<p>Mice were treated with Ad-m IL-10/Ad-m IGF-1. Pancreata were collected at 3 weeks after treatment...
<p>Composition of the insulitic lesion in 4-wk old diabetes-prone (islets from 5 mice), 12-wk old in...
Although insulin-dependent diabetes mellitus (IDDM) results from irreversible loss of beta cells, th...
<p>A Representative islets showing insulin (red) and Ki67 (green, indicated by arrows), insulin (red...
<p>Histology of representative pancreas sections of NOD mice before (at the commencement of autoimmu...
Prophylactic insulin treatment has been shown to have beneficial effects in type 1 diabetes, both in...
(A) Representative images of the pancreatic tissues from different groups were examined using H&E st...
<p>Representative frozen sections from a 3 week old female pre diabetic NOD mouse without insulitis ...
<p>Four weeks after the cessation of OA treatment, fresh islets were isolated from T2D mice treated ...
<p>Mice were treated with a treat-to-target insulin therapy for a month and tested with intraperiton...
<p>Representative images of pancreas section stained for Ki67 of control group (A) and HFD-PBS (B), ...