Identification of STEC strains in human gut metagenomes.

<p>Three human gut metagenome datasets [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117711#pone.0117711.ref025" target="_blank">25</a>], one of them without (1122) and two with STEC infection (2535, 2638), were analyzed with MicrobeGPS. MicrobeGPS identified one <i>E. coli</i>–related candidate in each dataset. In the datasets with STEC infection, MicrobeGPS finds the highest GDV scores for different STEC strains, showing almost perfect agreement between the sequenced organism and reference genome. In dataset 1122, MicrobeGPS only finds other <i>E. coli</i> strains with much lower GDV scores, indicating correctly that this sample was not infected with STEC.