The mRNA expression levels of <i>Cosmc.</i>

<p>The mRNA expression levels of <i>Cosmc</i> by RT-PCR. Samples are B lymphocytes from peripheral blood of the 3 groups (IgAN patients, n = 26; other renal disease patients, n = 11; healthy children participants, n = 13). Error bars represent s.e.m. and * * * for p-value ≤ 0.001. (a) <i>Cosmc</i> mRNA expression in 3 groups after 48 hours culturing. (b) <i>Cosmc</i> mRNA expression in 3 groups after 48 hours culturing with IL-4 (10 ng/ml). (c) <i>Cosmc</i> mRNA expression in 3 groups after 48 hours culturing with AZA (1 umol/l). (d) <i>Cosmc</i> mRNA expression in 3 groups treated or not (beige) with IL-4 (green) or AZA (blue). (e, f) Compared to plain medium, IL-4 or AZA caused the alteration of <i>Cosmc</i> mRNA levels in the other two groups. The mRNA data in Figure was the relative quantification of the ratio of Cosmc/GAPDH in each sample.