Performance scores of different prediction methods.

<p>^aHumVar trained PolyPhen-2. The performance of this version was better than for HumDiv trained PolyPhen-2 (data not shown).</p><p>^bPerformance scores are computed by using the predicted variants at 0.95 confidence level.</p><p>^cPerformance scores inside parentheses are for the predictor when the unreliable cases are included.</p><p>^dSens, Sensitivity; Spec, Specificity; Acc, Accuracy; OPM, Overall performance measure.</p><p>Performance scores of different prediction methods.