(A) Mosaic plot representing the probabilities of transition from H1hesc chromatin states to Nhdfad chromatin states.

<p>The width of columns corresponds to the proportion of chromatin states in H1hesc. The segmentation for the <i>i</i>^<i>th</i> column follows the proportion of windows in state ECi in H1hec that become Cj in Nhdfad. In other words, if we take the first pink rectangle of the first column, its width is proportional to the probability for a 100 kb window to be in chromatin state EC1 in H1hesc and its height is proportional to the probability for a 100 kb window to be in C1 in Nhdfad given that it is in EC1 in H1hesc. The area of this rectangle (product of the previously mentioned probability) is proportional to the probability for a window to be in state EC1 in ESC and C1 in Nhdfad. (B) Same as (A) for the chromatin state changes from the cell line K562 towards Nhdfad.