Gene-gene interactions among genes neighboring SNPs in high LD with prostate cancer risk alleles.

<p>A total of 78 unique genes contained or were located within 100 Kb of SNPs in high LD (r²>0.80). Gene-gene interactions were identified using the Ingenuity Pathway Analysis software. The most significant functional network demonstrating connectivity between genes was identified as having a potential function in <i>Cancer</i>, <i>Cellular Growth and Proliferation</i>, <i>and Organismal Injury and Abnormalities</i>. Gene products shaded in gray represent genes originating from the gene list.