Immunohistochemical analyses of IL-6 in high-grade serous ovarian cancer tissues.
- Aki Isobe (689884)
- Kenjiro Sawada (689885)
- Yasuto Kinose (689886)
- Chifumi Ohyagi-Hara (689887)
- Erika Nakatsuka (689888)
- Hiroshi Makino (484869)
- Tomonori Ogura (689889)
- Tomoko Mizuno (308626)
- Noriko Suzuki (315835)
- Eiichi Morii (162029)
- Koji Nakamura (689890)
- Ikuko Sawada (689891)
- Aska Toda (689892)
- Kae Hashimoto (689893)
- Seiji Mabuchi (689894)
- Tsuyoshi Ohta (689895)
- Ken-ichirou Morishige (689896)
- Hirohisa Kurachi (689897)
- Tadashi Kimura (392934)
Publication date
February 2015
DOIAbstract
<p>Serial sections of stage III high-grade serous ovarian cancer tissues were immunostained with anti-IL-6 antibody (A, C) and anti-CD-68 antibody (B, D). IL-6 was strongly expressed in stroma, while cancer cells little expressed IL-6. (A, B) Sections from a 56 year-old female with stage IIIC high-grade serous ovarian cancer. (C, D) sections from a 63 year-old female with stage IIIC high-grade serous ovarian cancer. CD68 staining identified macrophages. Arrows indicate macrophages. Arrowheads indicate ovarian cancer cells. Original magnification, x100 (upper panels), and x400 (bottom panels). Black bar; 200 μm, red bar; 50 μm.</p
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