DNA damage response-related parameters and associated Wilcoxon rank-sum tests in platinum-sensitive (A2780) and platinum-resistant (A2780/C30) cell lines.

<p>¹cells that are defined as having more than 5 foci per cell, expressed as a fraction of 100</p><p>²Olive Tail Moment (OTM) values, arbitrary units</p><p>³AUC values, expressed as (% of γH2AX positive staining cells) x (carboplatin dose)</p><p>⁴AUC values (expressed as OTM x carboplatin dose)</p><p>⁵t_1/2 for γH2AX foci removal, in h</p><p>⁶t_1/2 values for carboplatin-induced damage repair, in h</p><p>⁷apoptosis rates expressed as doses of carboplatin inducing apoptosis (as defined in the Materials and Methods section)</p><p>⁸AUC values, expressed as (% of pan-nuclear staining cells) x (carboplatin dose)</p><p>⁹Wilcoxon rank-sum tests.</p><p>DNA damage response-related parameters and associated Wilcoxon rank-sum tests in platinum-sensitive (A2780) and platinum-resistant (A2780/C30) cell lines.