Examination of Ppc-1-treated mice.

<p>(A) Cross sections were prepared of fixed kidney and liver tissues from mice in the control and Ppc-1 treated (0.8 mg/week/kg) groups and stained with hematoxylin-eosin. Representative images are shown; no significant differences were detected between the two groups. (B) Daily food intake in 4 groups was recorded throughout the experiments. (C) Body surface temperature was monitored with an infrared thermometer following a single injection of Ppc-1 (0.8 mg/kg).