<p>The ability of p53 proteins to transactivate from the five natural REs at different expression levels was measured culturing yeast cells at 24°C (white bars) or 37°C (black bars) in media containing the indicated amount of galactose. Data obtained at 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116177#pone.0116177.g002" target="_blank">Fig. 2</a>) were re-plotted (gray bars) for comparison. The experiments were performed and data were analyzed and presented as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116177#pone.0116177.g002" target="_blank">Fig. 2</a>.</p
Cells need to preserve genome integrity despite varying cellular and physical states. p53, the guard...
Wild-type and mutant p53 proteins exhibit opposing activities in respectively suppressing and promot...
BACKGROUND: The protein p53 plays an active role in the regulation of cell cycle. In about half of h...
<p>Results were obtained as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/jo...
<p>Transactivation potentials for the ten REs tested are presented as radar plot graphs in Log<sub>1...
The finding that the well-known mammalian P53 protein can act as a transcription factor (TF) in the ...
<p>Three isogenic yeast strains were used, two with p53 targets sites (XA and XG) and one without a ...
<div><p>Co-evolution of transcription factors (TFs) with their respective <i>cis</i>-regulatory netw...
Background: The protein p53 plays an active role in the regulation of cell cycle. In about half of h...
The human p53 protein acts mainly as a stress inducible transcription factor transactivating severa...
(A) Similar to 1D, this time plates were incubated at 25°C, 30°C or 34°C for 40h. (B) Protein levels...
The protein p53 plays an active role in the regulation of cell cycle. In about half of human cancers...
<p>A representative immunoblot of p53 protein expression in cultured granulosa cells shows dose-depe...
<p>(A) Fivefold serial dilutions of yeast cells (BY4741 background) expressing p53<sup>+</sup>, p53<...
Symmay The tumour-suppressor protein p53 is a metal-binding transcription factor with sequence-speci...
Cells need to preserve genome integrity despite varying cellular and physical states. p53, the guard...
Wild-type and mutant p53 proteins exhibit opposing activities in respectively suppressing and promot...
BACKGROUND: The protein p53 plays an active role in the regulation of cell cycle. In about half of h...
<p>Results were obtained as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/jo...
<p>Transactivation potentials for the ten REs tested are presented as radar plot graphs in Log<sub>1...
The finding that the well-known mammalian P53 protein can act as a transcription factor (TF) in the ...
<p>Three isogenic yeast strains were used, two with p53 targets sites (XA and XG) and one without a ...
<div><p>Co-evolution of transcription factors (TFs) with their respective <i>cis</i>-regulatory netw...
Background: The protein p53 plays an active role in the regulation of cell cycle. In about half of h...
The human p53 protein acts mainly as a stress inducible transcription factor transactivating severa...
(A) Similar to 1D, this time plates were incubated at 25°C, 30°C or 34°C for 40h. (B) Protein levels...
The protein p53 plays an active role in the regulation of cell cycle. In about half of human cancers...
<p>A representative immunoblot of p53 protein expression in cultured granulosa cells shows dose-depe...
<p>(A) Fivefold serial dilutions of yeast cells (BY4741 background) expressing p53<sup>+</sup>, p53<...
Symmay The tumour-suppressor protein p53 is a metal-binding transcription factor with sequence-speci...
Cells need to preserve genome integrity despite varying cellular and physical states. p53, the guard...
Wild-type and mutant p53 proteins exhibit opposing activities in respectively suppressing and promot...
BACKGROUND: The protein p53 plays an active role in the regulation of cell cycle. In about half of h...