Transient activation of Src depresses FAT4 gene expression and induces tumor transformation in MCF-10A cells.

Takao Ito (420509)
Hiroaki Taniguchi (91492)
Kousuke Fukagai (674529)
Shota Okamuro (674530)
Akira Kobayashi (2156932)

Publication date

February 2015

DOI

10.1371/journal.pone.0118336.g001

Abstract

A. Images show morphological changes of MCF-10A v-Src:ER cells treated with 1 μM TAM for 36 h. Black bars, 100 μm. B. WST-1 Assay in TAM-treated cells (48 h) (mean ± SD, n = 3, ** indicates P < 0.01). C. Soft Agar Colony Formation Assay in TAM-treated cells (72 h) (mean ± SD, n = 4). Images show cell colonies. Black bars, 1 mm. D. RT-qPCR analysis of FAT4 mRNA expression levels in TAM-treated cells for the indicated times (mean ± SD, n = 3).</p

Extracted data

We use cookies to provide a better user experience.

Data Protection

Transient activation of Src depresses <i>FAT4</i> gene expression and induces tumor transformation in MCF-10A cells.

Abstract

Extracted data

Transient activation of Src depresses <i>FAT4</i> gene expression and induces tumor transformation in MCF-10A cells.

Abstract

Extracted data

Related items

Related items