Migration trajectories of dHL-60 cells tracked from hours 4–6 after the cells are embedded into the four different basal lamina matrices.

<p>The starting point of all trajectories is shifted to the origin for clarity, and the end point is marked by a dot. The average start-to-end distance (Euclidean distance) travelled by the cells and the respective standard deviation is denoted by <i>ED</i>. The fraction of cells with an <i>ED</i> greater than <i>ED</i> = 105.5 μm (red circle) is denoted by <i>f</i>. (e) Comparison of the migration velocity of dHL60 cells in different ECM gels. The red line denotes the median of the velocity distribution, the box includes 25% of the observed velocities above and below this median, respectively. The remaining 25% of slower as well as the 25% of faster cells are indicated by the dashed lines. Outliers are denoted by a red cross.