<i>In vivo</i> beta-glucuronidase activity of tumors treated with <i>E. coli</i> (lux/βG).

<p>(A) NOD/SCID mice bearing HCT116 tumors were i.v injected with 4 x 10⁷ c.f.u. <i>E. coli</i> (lux) or <i>E. coli</i> (lux/βG). After 4 days, 500 μg FDGlcU was i.v. injected into the mice. After 30 min, the luminescence (representing bacterial numbers) and fluorescence (representing beta-glucuronidase activity) in tumors were detected on an IVIS Spectrum (n = 3). (B) The mean luminescence and fluorescence intensities in tumors are shown. Unit is photons sec^-1cm^-2sr^-1. Bars, s.d. * P < 0.05.