Astrocytes of murine CNS primary cultures are targets of <i>Trypanosoma cruzi</i> infection.

<p>(A) Experimental scheme showing that cultures of astrocytes were infected at MOI of 1:1 or 10:1 and analyzed 4 and 24 hours post-infection (p.i.). (B) Representative pictures of noninfected and <i>T. cruzi</i>-infected astrocytes at 4 hours of infection. (C) The percentage of infected cells (D) and the number of parasites per cells were analyzed. Data are presented as mean ± SEM of triplicates. *, <i>p</i> < 0.05 and ***, <i>p</i> < 0.001comparing MOI 1:1 with MOI 10:1 in each analyzed intervals; ^#, <i>p</i> < 0.05, ^##, <i>p</i> < 0.01 and ^###, <i>p</i> < 0.001 comparing 4 hours with 24 hours in each studied MOI.