<i>In vitro</i> binding studies of IONP.

<p>(<b>A</b>) Dose response rHER2 binding curves for 30 nm IONP-Tfab (closed circles) and 30 nm IONP-Mal (open squares). (<b>B</b>) Dose response rHER2 binding curves for 100 nm IONP-Tfab (closed circles) and 100 nm IONP-Mal (open squares). (<b>C</b>) Binding of HER2+ breast cancer cells for 30 nm IONP-Tfab and 30 nm IONP-Mal, both dosed at 100 μg/ml. (<b>D</b>) Binding of HER2+ breast cancer cells for 100 nm IONP-Tfab and 100 nm IONP-Mal, both dosed at70 μg/ml. Error bars represent standard deviation.