Correlations in spontaneous patterns of calcium activity.

<p>(A) Bars show mean pairwise correlation between calcium time series of all simultaneously recorded pairs of neurons. (B) Pairwise correlations as a function of spatial distance between cell bodies (Red: Awake, r = -0.061, p < 10^–10; Blue: Anesthesia, r = -0.073, p < 10^–10; n = 26350). (C) Pairwise correlations in spontaneous activity as a function of similarity in preferred direction of orientation-tuned cells (Red: Awake, r = -0.07, p = 0.04; Blue: Anesthesia, r = -0.09, p = 0.008; n = 846). (D) Power spectrum of oscillations in the baselined ΔF/F neuropil signal. (E) Power spectrum of oscillations in neuropil contamination-corrected ΔF/F calcium time series of all simultaneously recorded neurons. (F) Cross-spectrum coherence between neuropil contamination corrected ΔF/F calcium time series of all neurons and the simultaneously recorded, baselined ΔF/F neuropil signal. (G) Cross-spectrum coherence between neuropil contamination corrected ΔF/F calcium time series of all simultaneously recorded pairs of neurons. For each plot, the red line shows data recorded in awake mice, the blue line data from recordings under anesthesia. All values are mean ± SEM, ** p < 0.001, *** p < 10^–7.