Blockage of DJ-1 knockdown-induced IL-1β overexpression by NF-κB inhibitor in RAW cells.

<p>Quantitative RT-PCR showed that there was a higher level of IL-1β transcript in RAW 264.7 cells with DJ-1 knockdown as compared to control cells, which was partially reversed by treatment with NF-κB inhibitors PDTC, but not by redox inhibitors NAC and DPI. Data were presented as mean ± S.E.M. n = 3 for each group, * p < 0.05 compared with pLKO.1 control group, # p< 0.05 compared with DJ-1-shRNA control group.