Kaplan-Meier plots showing differences in survival of C57/BL/6 mice after intra-tracheal challenge with <i>P. gingivalis, P. gingivalis</i> plus pyocyanin, PBS, and PBS plus pyocyanin.

<p>Mice (10 animals per group) were inoculated with 3×10⁹ CFU of wild-type <i>P. gingivalis</i> W83 (Pg) or <i>P. gingivalis</i> plus 40 μg pyocyanin (Pg+PCN) into the lungs <i>via</i> the trachea. Control groups were challenged with PBS or with PBS plus 40 μg pyocyanin (PCN). The survival of mice was monitored during whole time of procedure. Log-rank test, n = 10 in all cases, **<i>P</i><0.01 and ***<i>P</i><0.001 for control PBS or PBS+PCN-inoculated, and <i>P. gingivalis</i>- or <i>P. gingivalis</i>+PCN-inoculated animals, respectively.