Effects of BSP deletion on the time-course of osteoblast marker and SIBLING expression in standard density MCC cultures.
- Guenaelle Bouet (5662099)
- Wafa Bouleftour (562282)
- Laura Juignet (695432)
- Marie-Thérèse Linossier (695433)
- Mireille Thomas (562285)
- Arnaud Vanden-Bossche (562284)
- Jane E. Aubin (90467)
- Laurence Vico (90466)
- David Marchat (695434)
- Luc Malaval (90454)
Publication date
February 2015
DOIAbstract
<p>(A-D) Time-course of expression of osteoblast-associated gene: osteocalcin (OCN), type 1 collagen (Col1α1), alkaline phosphatase (ALP), osterix (OSX) and Runx2 and SIBLING genes: osteopontin (OPN), bone sialoprotein (BSP), DMP1 and MEPE at successive time-points of BSP+/+ (A, C) and BSP-/- (B, D) MCC cultures. The arrow marks the appearance of bone nodules. N = 3 dishes/group. *: p< 0.05 vs time-matched BSP+/+; #: p<0.05 vs D3 to D14. Mann-Whitney U Test.</p
Add to ORKG