Overexpression of PTEN-Long inhibits cell migration and reduces cell invasion.

<p><b>A</b>, 786-0 cells stably expressing indicated proteins were subjected to <i>in vitro</i> wounding and followed by phase-contrast imaging. The fields in between the white lines indicate the wound track. The scale bar represents 20 µm. <b>B</b>, The number of cells migrated in the wound track from 6 random separate fields were counted for each cell and expressed as a mean ± SD (error bars). <b>C</b>, Invasive properties of 786-0 cells were inhibited by 30% by PTEN overexpression and by 25% by PTEN-Long overexpression, as compared to empty vector control cells.