Effect of XGB on serum BAs concentration in wild-type and <i>Tgr5</i>^-/- mice fed a chow diet.

<p>Blood specimens were obtained at the middle of the light and dark phases of the diurnal cycle to 5–6 wild—type and 4–5 <i>Tgr5</i>^-/- mice in each group of animals. White bars represent sham—operated mice and black bars represent mice subjected to XGB. Panel A shows total serum BAs concentration. Primary and secondary serum BAs concentrations are shown in panels B and C, respectively. Conjugated and unconjugated serum BAs levels are shown in panels D and E, respectively. Values represent the mean ± S.E.M. *p<0.01.