Effect of XGB on biliary BAs and cholesterol secretion rates in wild-type and <i>Tgr5</i>^-/- mice.

<p>Panel A represents biliary BAs secretion rates and panel B represents biliary cholesterol secretion rates measured 40 to 45 days after XGB or sham operation. Bile fistulas were established and bile flow was measured at the middle of the light phase of the diurnal cycle. White bars represent sham—operated mice and black bars represent mice subjected to XGB. There were 5 to 8 animals in each group. Values represent the mean ± S.E.M. *p<0.02; ^#p <0.05 compared with the wild type animals.