Fiber counts and cross-sectional areas in FA cardiomyopathy.

<p>(a) FA (patient FA2, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116396#pone.0116396.t001" target="_blank">Table 1</a>), (b) normal control. Transverse Brazilin-stained sections of VS were photographed at a magnification of 200X, and analyzed for fiber density and cross-sectional area within a field of 0.15 mm². (a) FA: The section shows paucity of fibers, hypertrophy, irregular contours, size variability, and endomysial thickening. The total number of fibers/0.15 mm² is 73, corresponding to 487/mm². The mean cross-sectional area is 804 μm² (range, 37–3953). (b) Normal control: Fibers are much smaller. The total number of fibers/0.15 mm² is 337, corresponding to 2247/mm². The mean cross-sectional area is 249 μm² (range, 24–664). Bars, 50 μm.