Microbiological characteristics of patients with recurrent invasive pneumococcal disease.

<p>P, patient identification; ST, sequence type by Multi-locus sequence typing; MDR, Multi-drug resistant strain; PCV-7, 7-valent polysaccharide-protein conjugate vaccine; PCV 13, 13-valent polysaccharide-protein conjugate vaccine; PPV-23, 23-valent pneumococcal polysaccharide vaccine; CSF, cerebrospinal fluid; NA, Not available; MIC, minimal inhibitory concentration; Pen, penicillin; Ery, erythromycin; Cm, chloramphenicol; Tet, tetracycline; Ctx, Cefotaxime; Bold text, resistant strain according to MICs for <i>Streptococcus pneumonia</i>. EUCAST Clinical Meningeal Breakpoints.</p><p>^aNA, ST were not available in episodes identified only by PCR.</p><p>Microbiological characteristics of patients with recurrent invasive pneumococcal disease.