Miniature inhibitory postsynaptic currents (mIPSCs) are similar in control, stress-susceptible and-resilient rats.

<p>Miniature IPSCs (mIPSCs) reflect functional properties of single GABAergic synapses under conditions of unitary GABA vesicle release, achieved by blocking action potentials with 1 μM tetrodotoxin (TTX). A. Traces displaying the average mIPSC waveform in unchallenged control, stress-susceptible and stress-resilient animals. B. Average mIPSC parameters including frequency, amplitude, decay time constants and 10–90% rise-time showed no differences (<i>P</i> > 0.05) between groups (control n = 13 cells/4 rats; stress-susceptible n = 19 cells/4 rats; resilient n = 11 cells/4 rats), indicating that synaptic GABA_A receptor properties in granule cells are unaltered following CMS.