γδ T cell control of MCMV infection is associated with reduced organ damage.

<p><b>A.</b> TCRδ^−/−, TCRα^−/−, CD3ε^+/− and CD3ε^−/− mice were infected i.p. as indicated in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004702#ppat.1004702.g001" target="_blank">Fig. 1A</a>. 3 mice/group were bled at days 0, 3, 7, 15, 21 and just before death for biochemical analyses of AST and ALT in serums. The experiment was repeated twice and data obtained for one representative mouse/group are shown. † death of CD3ε^−/−. <b>B.</b> TCRα^−/− and CD3ε^−/− mice were uninfected, or i.p. infected with 2.10³ pfu of MCMV. Uninfected and Day 22-infected mice were sacrificed and the liver and lungs were embedded in paraffin for HES staining. Apoptotic hepatocytes are shown (arrowheads). Scale bar = 200 mm. Magnifications are indicated in the right-hand side of the figure. The data are from one representative of 3 mice for each condition.