TNBS-induced acute and chronic colitis for Balb/c mice (n = 12).

<p>(A) Protocol. In acute colitis, mice received TNBS (1.0 mg in 45% ethanol) on day 0 and were sacrificed on day 4. In chronic colitis, mice received TNBS (1.0–2.3 mg) at one week intervals and were sacrificed on week 8. (B) Body weight changes measured through to week 8. Comparison of body weight between normal and TNBS on day 49, to determine ability to recover body weight, **p < 0.01