Univariate sensitivity analyses: Pediatric life expectancy.

<p>Undiscounted pediatric life expectancies for <i>laboratory</i> and <i>POC</i> testing are shown (maternal life expectancies do not differ substantially by testing strategy, and so are excluded from the figure). <i>POC</i> “test and result return” is defined as the product of (proportion of HIV-identified women undergoing CD4 testing) * (proportion of CD4-tested women receiving CD4 results). For <i>POC</i> sensitivity and <i>POC</i> “test and result return,” life expectancies are shown at the threshold values at which <i>POC</i> testing no longer results in a higher life expectancy compared to <i>laboratory</i> testing. For <i>POC</i> specificity, life expectancy increases as specificity decreases, so no such threshold exists; results are shown at 50%, 80%, and 100%, as examples. The horizontal dotted line shows the undiscounted pediatric life expectancy under the base case laboratory conditions. Left panel: base case; middle panel: low laboratory access scenario; right panel: sensitivity analyses on <i>POC</i> parameters. <b>Abbreviations</b>: <i>POC</i>: point-of-care testing.