<p>Abbreviations: COX: cyclooxygenase; CYP-450: cytochrome P–450; DiHETEs: dihydroxyeicosatetraenoic acids; EETs: epoxyeicosatrienoic acids; HETE: hydroxyeicosatetraenoic acid; HODE: hydroxyoctadecadienoic acid; LOX—lipoxygenase, LTX: lipoxin, PG: prostaglandin; TX: thromboxane.</p
<p>Dashed lines indicate steps consisting of multiple enzyme-catalyzed reactions. Symbols: HMG-CoA, ...
Introduction to the pharmacological design The effects of PGs and LTs in the physiopathology of infl...
The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key t...
<p>ARA is metabolized by three enzyme families, cyclooxygenase (COX), lipoxygenase (LOX), and cytoch...
The generation of prostaglandins and other oxygenated metabolites of arachidonic acid (AA) is a comp...
CYCLOOXYGENASE (COX), also represented as prostaglan-din H synthase, is one of the key enzymes in co...
Cyclooxygenase (COX) converts arachidonic acid into prosta-glandin H2, which is the rate-limiting st...
Prostaglandins are a diverse group of locally acting hormones that mediate a variety of physiologic ...
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandi...
Arachidonic acid (AA) reaction with cyclooxygenase (COX) and lipoxygenases (LOX) yield eicosanoids t...
A: Changes in the profile of LOX-dependent hydroxy-metabolites of AA. B: Levels of 11-HETE. C: Level...
AbstractLipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding hydropero...
[[abstract]]Eicosanoids comprise a large array of small-molecular-weight compounds that are synthesi...
A: Levels of ALA hydroxy-metabolites of LOX pathway. B. Changes in the profile of LOX-dependent hydr...
Arachidonic acid (AA), a 20 carbon chain polyunsaturated fatty acid with 4 double bonds, is an integ...
<p>Dashed lines indicate steps consisting of multiple enzyme-catalyzed reactions. Symbols: HMG-CoA, ...
Introduction to the pharmacological design The effects of PGs and LTs in the physiopathology of infl...
The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key t...
<p>ARA is metabolized by three enzyme families, cyclooxygenase (COX), lipoxygenase (LOX), and cytoch...
The generation of prostaglandins and other oxygenated metabolites of arachidonic acid (AA) is a comp...
CYCLOOXYGENASE (COX), also represented as prostaglan-din H synthase, is one of the key enzymes in co...
Cyclooxygenase (COX) converts arachidonic acid into prosta-glandin H2, which is the rate-limiting st...
Prostaglandins are a diverse group of locally acting hormones that mediate a variety of physiologic ...
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandi...
Arachidonic acid (AA) reaction with cyclooxygenase (COX) and lipoxygenases (LOX) yield eicosanoids t...
A: Changes in the profile of LOX-dependent hydroxy-metabolites of AA. B: Levels of 11-HETE. C: Level...
AbstractLipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding hydropero...
[[abstract]]Eicosanoids comprise a large array of small-molecular-weight compounds that are synthesi...
A: Levels of ALA hydroxy-metabolites of LOX pathway. B. Changes in the profile of LOX-dependent hydr...
Arachidonic acid (AA), a 20 carbon chain polyunsaturated fatty acid with 4 double bonds, is an integ...
<p>Dashed lines indicate steps consisting of multiple enzyme-catalyzed reactions. Symbols: HMG-CoA, ...
Introduction to the pharmacological design The effects of PGs and LTs in the physiopathology of infl...
The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key t...