Heat map and unsupervised hierarchical clustering for disease aetiology.

<p>The clustering is performed on top 50 miRNAs with highest standard deviation between groups and groups with three or more members. Samples were grouped according to the disease aetiologies of the patients: Group 1: Coronary artery disease (red), Group 2: Mitral valve insufficiency (blue), Group 3: Aortic stenosis (darkgreen), Group 5: Other cardiovascular disease (orange), and Group 7: Coronary artery disease and aortic stenosis (brown). The normalized (dCp) values were used for the analysis. The colour scale illustrates the relative expression level of miRNAs across all samples: red colour represents an expression level above mean, blue colour lower than the mean. Missing values are shown in grey.