Principal component analysis of transcription factor expression profiles from SIV-specific MHC tetramer-sorted CD8⁺ T cells and sorted CD8⁺ T cell subsets.

<p>(<b>A</b>) Plot of principal components 1 vs. 2, and 2 vs. 3 for each of the expression profiles assessed in sorted naïve and memory CD8⁺ T cell subsets isolated from healthy control animals (n = 5), and SIV-specific MHC tetramer-sorted CD8⁺ T cells isolated from animals (n = 4) at week 5 or week 20 following SIVΔnef vaccination. Principal components 1, 2 and 3 explain 92% of cumulative total variance. (<b>B</b>) PCA loading factors for each transcription factor.