<p>Values are given as median and range. Plasma levels of enrofloxacin, its active metabolite ciprofloxacin, erythromycin, and rifampicin were highest 3 and 5 dpi, whereas levels of azithromycin reached their maximum 10 dpi. Different letters (a, b) indicate statistically significant differences in antibiotic concentration in plasma and tissue between groups treated with or without rifampicin on the same day (<i>P</i> < 0.05, Mann-Whitney U-test).</p><p>Concentrations of antimicrobial substances in blood plasma and tissue samples.</p
<p>Sputum neutrophil proportion, CXCL8 levels and bacterial load before and following add-on azithro...
In spite of the development and wide use of antibiotics, pneumonia is still the leading cause of inf...
Over the last decades, numerous papers have appeared-and still are appearing-that describe concentra...
Most of the successful non-surgical management of abdominal abscesses is based upon the presence of ...
Dried blood spot (DBS) antibiotic assays can facilitate pharmacokinetic (PK)/pharmacodynamic (PD) st...
Abstract: Most of the successful non-surgical management of abdominal abscesses is based upon the pr...
OBJECTIVES: The administration of antibacterial agents should be optimized on the basis of their dis...
none1noPrompt optimal antimicrobial treatment in critically ill patients is mandatory and must be ac...
The pharmacokinetic/pharmacodynamic (PK/PD) indices useful for predicting antimicrobial clinical eff...
Prompt optimal antimicrobial treatment in critically ill patients is mandatory and must be achieved ...
To be effective, antibacterials must be active against microorganism(s) and reach sufficient concent...
<p>AZM, azithromycin; FOM, fosfomycin; NFLX, norfloxacin; KM, kanamycin; OFLX, orfloxacin; CPFX, cip...
International audienceAims: Rifampicin represents the key antibiotic for the management of osteoarti...
It has been shown that protein binding, temperature, and pH influence in vitro pharmacodynamic (PD) ...
<p>Antimicrobial agents and dosages utilized in the main trial. Equivalent dosages in mice and human...
<p>Sputum neutrophil proportion, CXCL8 levels and bacterial load before and following add-on azithro...
In spite of the development and wide use of antibiotics, pneumonia is still the leading cause of inf...
Over the last decades, numerous papers have appeared-and still are appearing-that describe concentra...
Most of the successful non-surgical management of abdominal abscesses is based upon the presence of ...
Dried blood spot (DBS) antibiotic assays can facilitate pharmacokinetic (PK)/pharmacodynamic (PD) st...
Abstract: Most of the successful non-surgical management of abdominal abscesses is based upon the pr...
OBJECTIVES: The administration of antibacterial agents should be optimized on the basis of their dis...
none1noPrompt optimal antimicrobial treatment in critically ill patients is mandatory and must be ac...
The pharmacokinetic/pharmacodynamic (PK/PD) indices useful for predicting antimicrobial clinical eff...
Prompt optimal antimicrobial treatment in critically ill patients is mandatory and must be achieved ...
To be effective, antibacterials must be active against microorganism(s) and reach sufficient concent...
<p>AZM, azithromycin; FOM, fosfomycin; NFLX, norfloxacin; KM, kanamycin; OFLX, orfloxacin; CPFX, cip...
International audienceAims: Rifampicin represents the key antibiotic for the management of osteoarti...
It has been shown that protein binding, temperature, and pH influence in vitro pharmacodynamic (PD) ...
<p>Antimicrobial agents and dosages utilized in the main trial. Equivalent dosages in mice and human...
<p>Sputum neutrophil proportion, CXCL8 levels and bacterial load before and following add-on azithro...
In spite of the development and wide use of antibiotics, pneumonia is still the leading cause of inf...
Over the last decades, numerous papers have appeared-and still are appearing-that describe concentra...