Increased resistance in PI3Kγ^-/- mice infected with PbA.

<p>Percentage of survival in PbA-infected mice <b>(A)</b>. C57BL/6 WT (solid lines, n = 5) and PI3Kγ^-/- mice (dashed lines, n = 6). The survival curve of PI3Kγ^-/- was significantly different of WT, with *p<0.05. Percentage of ECM incidence in infected mice <b>(B)</b> based on typical neurological symptoms of ECM, with *p<0.05 between groups. Parasitemia levels <b>(C)</b> from day 3 p.i. up to day 12 p.i., without differences between infected groups. Parasitemia was expressed as mean ± SD. Representative results from 2 independent experiments.