<p>A. Simplified metabolism of flurbiprofen in humans. B. FLB (R = H) and OHF (R = OH) acylglucuronides with positions of the glucuronic acid moiety.</p
Loxoprofen, a propionic acid derivative, non-steroidal anti-inflammatory drug (NSAID) is a prodrug t...
The kinetics of 2-acetylaminofluorene (AAF) metabolism have been studied in liver microsomes from fo...
Incorporation of fluorine in a drug can dramatically affect its metabolism and methods to assess the...
<p>Structures of ibuprofen, flurbiprofen and the metabolites investigated in the present study.</p
Flurbiprofen is a nonsteroidal anti-inflammatory drug used as a racemic mixture. Although glucuronid...
Several Streptomyces and Bacillus strains were examined for their ability to transform the anti-infl...
In drug design, one way of improving metabolic stability is to introduce fluorine at a metabolically...
1.Fluorine plays a key role in the design of new drugs and recent FDA approvals included two fluorin...
Male rats were given the nitrooxybutyl ester of flurbiprofen HCT1026 (15 mg/Kg) by oral administrati...
<p>Belinostat metabolism pathway in human plasma with glucuronidation of belinostat as the dominant ...
<div><p>Background</p><p>In addition to their effects upon prostaglandin synthesis, the non-steroida...
The phenylalkanoic acid derivative, flurbiprofen (2-[2-fluoro-4-biphenylyl]propionic acid), is a non...
Recent interest in the metabolism of glucuronic acid has been aroused mainly as a result of the real...
Flurbiprofen is a fluorinated non-steroidal anti-inflammatory pharmaceutical. While flurbiprofen is...
and in combination with alfuzosin for the management of lower urinary tract symptoms. Cent European ...
Loxoprofen, a propionic acid derivative, non-steroidal anti-inflammatory drug (NSAID) is a prodrug t...
The kinetics of 2-acetylaminofluorene (AAF) metabolism have been studied in liver microsomes from fo...
Incorporation of fluorine in a drug can dramatically affect its metabolism and methods to assess the...
<p>Structures of ibuprofen, flurbiprofen and the metabolites investigated in the present study.</p
Flurbiprofen is a nonsteroidal anti-inflammatory drug used as a racemic mixture. Although glucuronid...
Several Streptomyces and Bacillus strains were examined for their ability to transform the anti-infl...
In drug design, one way of improving metabolic stability is to introduce fluorine at a metabolically...
1.Fluorine plays a key role in the design of new drugs and recent FDA approvals included two fluorin...
Male rats were given the nitrooxybutyl ester of flurbiprofen HCT1026 (15 mg/Kg) by oral administrati...
<p>Belinostat metabolism pathway in human plasma with glucuronidation of belinostat as the dominant ...
<div><p>Background</p><p>In addition to their effects upon prostaglandin synthesis, the non-steroida...
The phenylalkanoic acid derivative, flurbiprofen (2-[2-fluoro-4-biphenylyl]propionic acid), is a non...
Recent interest in the metabolism of glucuronic acid has been aroused mainly as a result of the real...
Flurbiprofen is a fluorinated non-steroidal anti-inflammatory pharmaceutical. While flurbiprofen is...
and in combination with alfuzosin for the management of lower urinary tract symptoms. Cent European ...
Loxoprofen, a propionic acid derivative, non-steroidal anti-inflammatory drug (NSAID) is a prodrug t...
The kinetics of 2-acetylaminofluorene (AAF) metabolism have been studied in liver microsomes from fo...
Incorporation of fluorine in a drug can dramatically affect its metabolism and methods to assess the...
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