<p>Eosinophils isolated from peripheral blood of normal donors incubated with <b>(A)</b> HMGB1 alone or 10 ng/mL HMGB1 in combination with increasing concentrations of pro-survival cytokines <b>(B)</b> IL-5, <b>(C)</b> IL-13 or <b>(D)</b> GM-CSF for 48 hours and then evaluated with Violet live-dead for the assessment of viability.</p
<p>Murine macrophage-like RAW 264.7 cells were stimulated with LPS, and EGCG (10 µM) was added at 0,...
<p><b>A.</b> Mf survival in groups of PHIL (black squares) and C57Bl/6 (open circles) mice, followin...
<p>HEC slices were treated with HMGB1 (500 ng/ml) for 96 hrs. and then harvested for detection of pr...
<p>Eosinophils isolated from peripheral blood of normal donors incubated in the presence (open bars)...
HMGB1 is an alarmin that can stimulate the innate immune system alone or in a complex with other inf...
<p>Chemotaxis of peripheral blood eosinophils from normal donors evaluated in response to <b>(A)</b>...
<p><b>A–B:</b> RAW 264.7 cells were treated with the indicated amount of HMGB1 and IFN-γ for 18 hour...
Sepsis remains a significant health burden and a major clinical need exists for therapeutics to damp...
<p>Murine macrophage-like RAW 264.7 cells (Panel A, Panel C) or primary murine peritoneal macrophage...
<p>RAW 264.7 cells were treated with the indicated amount of HMGB1 for 24, 48 or 72 hours. <b>A:</b>...
<p>Human eosinophils were isolated from peripheral blood of normal donors. Surface expression of RAG...
<p>(A) HMGB1 was firstly extracted from effluent obtained after 24 h of cold storage and then treate...
Normodense human peripheral blood eosinophils were isolated under sterile conditions from the 22/23 ...
<p><b>A:</b> Timeline of the cell-based screening: RAW 264.7 cells were pre-treated with test compou...
<p>(A) C57BL/6 wild-type mice underwent trauma hemorrhage (TH) and were randomly resuscitated with e...
<p>Murine macrophage-like RAW 264.7 cells were stimulated with LPS, and EGCG (10 µM) was added at 0,...
<p><b>A.</b> Mf survival in groups of PHIL (black squares) and C57Bl/6 (open circles) mice, followin...
<p>HEC slices were treated with HMGB1 (500 ng/ml) for 96 hrs. and then harvested for detection of pr...
<p>Eosinophils isolated from peripheral blood of normal donors incubated in the presence (open bars)...
HMGB1 is an alarmin that can stimulate the innate immune system alone or in a complex with other inf...
<p>Chemotaxis of peripheral blood eosinophils from normal donors evaluated in response to <b>(A)</b>...
<p><b>A–B:</b> RAW 264.7 cells were treated with the indicated amount of HMGB1 and IFN-γ for 18 hour...
Sepsis remains a significant health burden and a major clinical need exists for therapeutics to damp...
<p>Murine macrophage-like RAW 264.7 cells (Panel A, Panel C) or primary murine peritoneal macrophage...
<p>RAW 264.7 cells were treated with the indicated amount of HMGB1 for 24, 48 or 72 hours. <b>A:</b>...
<p>Human eosinophils were isolated from peripheral blood of normal donors. Surface expression of RAG...
<p>(A) HMGB1 was firstly extracted from effluent obtained after 24 h of cold storage and then treate...
Normodense human peripheral blood eosinophils were isolated under sterile conditions from the 22/23 ...
<p><b>A:</b> Timeline of the cell-based screening: RAW 264.7 cells were pre-treated with test compou...
<p>(A) C57BL/6 wild-type mice underwent trauma hemorrhage (TH) and were randomly resuscitated with e...
<p>Murine macrophage-like RAW 264.7 cells were stimulated with LPS, and EGCG (10 µM) was added at 0,...
<p><b>A.</b> Mf survival in groups of PHIL (black squares) and C57Bl/6 (open circles) mice, followin...
<p>HEC slices were treated with HMGB1 (500 ng/ml) for 96 hrs. and then harvested for detection of pr...
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