Metabolic function is similar between control and GnIRKO mice.

<p>(A) Body weight in lean mice maintained on regular chow and DIO mice introduced high fat diet at 8 weeks of life. (B) Serum insulin and (C) serum leptin after a 6 hour fast in mice fed high fat diet for 12 weeks. (D) Glucose tolerance test. Values are mean ± SEM. n = 6–8 each group *, p <0.05.