NKp46(S) expression on CD56^dim NK cells after vaccination inversely correlates with IFN-γ secretion to A/PR8 restimulation.

<p>FACS analysis of NKp46 expression (MFI) on CD3⁻CD56^dim NK cells from PBMCs of both vaccinated and control subjects (left y-axis, blue). PBMCs restimulated ex vivo with or without A/PR8 were evaluated at 18 hours for IFN-γ secretion by gating on CD3⁻CD56^dim NK cells (right y-axis, red). NK responsiveness was calculated as: % A/PR8-stimulated IFN-γ⁺CD3⁻CD56^dim NK cells—% control IFN-γ⁺CD3⁻CD56^dim NK cells.